Available Thesis TopicsMSc/BSc Thesis: Development of Functional Liver Models and Advanced Analytical Methods for Small-Scale Tissue Characterization
Background: Three-dimensional (3D) scaffold-based cell cultures are increasingly used to mimic physiological liver tissue conditions in vitro. The mechanical properties of these liver models, including viscoelasticity and structural heterogeneity, strongly influence cellular behavior, viability, and metabolic activity. However, conventional rheological methods are often unsuitable for such small, irregular biological samples, limiting measurement accuracy and reproducibility. […]Background: Three-dimensional (3D) scaffold-based cell cultures are increasingly used to mimic physiological liver tissue conditions in vitro. The mechanical properties of these liver models, including viscoelasticity and structural heterogeneity, strongly influence cellular behavior, viability, and metabolic activity. However, conventional rheological methods are often unsuitable for such small, irregular biological samples, limiting measurement accuracy and reproducibility. […]
